Sterols and Sterolins - a
Natural Health Supplement

Natur-Leaf ® Ingredients

  • Wild African Potato Root
  • Lupine Sprouts
  • Fenugreek Sprouts
  • Barley Sprouts
  • Boswellia serrata
  • Soybean Sprouts
  • African Sunflower Sprouts
  • Phytosterol (40% Beta Sitosterol) from non-GMO soy
  • Vegetarian Capsule and rice concentrate


Each vegetarian capsule of Natur-Leaf ® contains 400 mg of a proprietary phytonutrients blend containing sterols/sterolins. The 400 mg of phytonutrients blend and the sterols/sterolins includes the whole plant sprouts, which have been ground and freeze-dried immediately after harvesting at a hydroponics farm in South Africa. All the nutrients of the plant sprouts are retained in the end-product. So, in addition to the sterols and sterolins, the vegetarian capsules contain vitamins, minerals, and other phytonutrients associated with the young plant sprout.

The ratio of the sterols to their glucosides (sterolins) in Natur-Leaf ® averages about 6:1. It varies a little because they are derived naturally in the plants we use. This ratio is important to understand because it is what is found in nature, with no introduction of outside glucosides (sterolins) to the sterols. Each 400 mg capsule of Natur-Leaf ® contains approximately 40 mg of sterols with 8 mg of sterolins.

In order to get the full immune-enhancing benefits of sterols, you also need the sterolins to provide the bioavailability. Without your body being able to absorb the sterols they are not of much benefit other than to reduce cholesterol absorption. The best ratio of sterols to sterolins, according to Karl Pegel, Ph.D. (arguably one of the foremost authorities on sterols/sterolins since 1968), is 10:1 or better. Natur-Leaf’s ratio is about 6:1.

Do not be confused with the imitation products that have been coming out on the market in the last couple of years (i.e. spreads, drinks, pills). Natur-Leaf ® not only has approximately 80 mg of sterols per serving size and helps block cholesterol absorption due to the sterols, but more importantly it also provides you with sterolins, a glucoside of the sterols which is needed for the sterols to be absorbed and useful to the immune system. Without the sterolins, you will miss the main health benefits of the sterols.

To the best of our knowledge, there is no other sterolin product on the earth which is more concentrated in its sterol/glucoside ratio than Natur-Leaf ®.

During these economically stressful times, it is tempting to let your health take a back seat in your priorities in life. However, adding health issues to your difficulties is not PRUDENT. Keep your immune system strong – give it the nutrition it needs. Take your Natur-Leaf® daily! Do not be “penny wise and pound foolish.”

The Holistic Lifestyle

Volume 1, number 2, September 2000
©Holistic International™ 2000


Phytosterols (plant sterols and sterolins , as well as campesterol and sigmasterol) are fatty components of plants which are stripped from the diet by food processing and cooking, and which support human health in many ways. Various combinations of sterols and sterolins have been shown to improve symptoms of benign prostatic hypertrophy (BPH)12, improve some autoimmune disorders16,17 lower cholesterol when taken with a meal18, and to possibly prove helpful in type II and type I diabetes. Women who get more phytosterols in their diet are less likely to develop breast cancer21, and phytosterols slow the growth and spread of human breast, prostate14, and colon15 cancer cells in animal and test tube models. They have anti-inflammatory powers23, and are powerful immune modulators21.

Unfortunately, most phytosterol products utilize a poor extraction process, which reduces their bioavailability and introduces an unnaturally low ratio of sterolins to sterols. The most readily available such product begins with a sterol extract from one source (pine oil), using an extraction method, which almost completely removes the natural sterolins, and then adds in sterolins separately from soy. The resulting amalgamation has one hundred times as much sterol as the more fragile sterolins, a ratio much lower than is found in whole foods: natural sources contain a 10% or better content of sterolins, with some foods providing as much as 80% sterolins by weight24. Such low ratios become even worse upon ingestion, because the body absorbs two to five times less sterolins than it does sterol24, so that a 100:1 sterol-to-sterolin mixture may actually provide as unbalanced a ratio as 200:1 or 500:1 in the body--ratios far lower than those required for optimal immune enhancement21.

These products are not useless, but they do not live up to the potential of a more natural phytosterol supplement. A ratio of one milligram of sitosterols to 5-10 milligrams of plant sterols is optimal, according to Dr. Karl Pegel of the University of Natal, one of the foremost authorities on the role of phytosterols in human nutrition. These ratios can be achieved by using a solvent-free, whole-food plant extraction process from sprouts. The higher content of sterolins in such extracts may increase the bioavailability of the whole mixture. As well, such extraction methods hold onto many health-promoting phytochemicals and vegetal trace minerals which are lost to more heavily processed products. Whole-food sprout extracts deliver a full spectrum of phytonutrients, in their optimal dosage, form, and ratios - as Nature intended.


12. Wilt TJ, MacDonald R, IshaniA. beta.sitosterol for the treatment of benign prostatic hyperplasia a systematic review BJU Int. 1999 Jun;83(9): 976-83.

13. Awad AR, Downie A, Fink CS, Kim U Dietary phytosterol inhibits the growth and metastasis of MDA-MB-231 human breast cancer cells grown in SCID mice. Anticancer Ret. 2000 Mar-Apr; 20(2A): 821-4.

14. von Holzt RL, Fink CS, Awad AB. beta-Sitosterol activates the sphingomyelin cycle and induces apoptosis in LNCaP human prostate cancer cells. Nutr Cancer. 1998; 32(1): 8-12.

15. Awad AR, von Holtz RL, Cone JP, Fink CS, Chin YC beta-Sitoterol inhibits growth of HT-29 human colon cancer cells by activating the sphingomyelin cycle. Anticancer Ret. 1998 Jan-Feb; 18(IA): 471-3.

16. Ramakrishanamacharya CH, Krisbnaswamy MR, Rosa RB, Viswanathan S. Anti-inflammatory efflcacy of Melothria madraspatana in active rheumatoid arthritis. Clin Rheumatol 1996 Mar; 15(2): 214-5.

17. Zorn J New aspects in rheumatism therapy. Experiences with a sitosterin- preparation in chronic polyarthritis. Med Welt. 1981 Jan 23;32(4): 135-8.

18. Law M. Plant sterol and stanol margarines and health. BMJ. 2000 Mar25; 320(7238):861-4.

19. Sutherland WH, Scott RS, Lintott CJ, Robertson MC, Stapely SA, Cox C Plasma non-cholesterol sterols in patients with non-insulin dependent diabetes mellitus. Horm Metab Res. 1992 Apr;24 (4):172 -5.

20. Ivorra MD, DO 'Con MP, Paya M, VillarA. Anti-hyperglycemica and insulin releasing effects of beta-sitosterol 3-B-D.glucoside and its aglycone beta-sitosterol. Arch Int Pharmacodyn Ther. 1988 April; 296:224-31.

21. Bouic PJ, Etsebeth 5, Liebenberg RW, Albrecht (Pegel K,Van Jaarsveld PP beta-sitosterol and beta-sitosterol glucoside stimulate human peripheral blood lymphocyte proliferation: implications for their use as an immunomodulatoryvitamin combination..Int J lmmunopharmacol 1996 Dec; 18U2):693-700.

22. Ronco A, De Stefani E, Boffttta F, Deneo-Pellegrini H, Mendilaharsu M, Leborgne F Vegetables, fruits, and related nutrients and risk of breast cancer: a case-control study in Uruguqy. Nutr Cancer 1999; 35(2): 111-9.

23. Gupta MB, Natb R, Srivastava N Shanker K, Kishor K, Bhargava KP. Anti-inflammatory and antipyretic activities of beta-sitosterol Plonta Med. 1980 Jan; 39(2): 157-63.

24. Pegel KH. The importance of sitosterol and sitosterolin in human and animal nutrition. S Afr J Sci. 1997 June; 93: 263-8.

25. Solen C, Ahrens EHJr, Grandy SM. Metabolism of beta-sitostosterol in man. J Clin Invest. 1970 May; 49(5): 952 -6 7.

Reprinted with Permission

Dr. Chris Morris, ND, the Clinical Director of Transformational Health states:

"Thus, if there is any family predisposition to major or minor health issues for patients, supplementation with sterols/sitosterolins would be beneficial as a means of prevention. But I'm not using the phytosterols just as protectors against some illness; instead, I apply them generally as a source of patient vitality".

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